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CONDITIONS · PCOS

PCOS makes it harder, not impossible.

PCOS is a hormonal and metabolic condition that makes ovulation irregular or stops it. Women with PCOS are usually not short of eggs; the task is to help one egg be released.

  • Common
  • Diagnosed with 2 of 3 signs
  • Most never need IVF
  • Weight first, then tablets
What happens in a PCOS ovaryPCOS: 1 many small follicles start growing; 2 none is picked to mature, so they stall part-grown; 3 no egg is released, no ovulation that month; 4 treatment helps one follicle mature and release its egg.PCOS OVARYWITH TREATMENT1Many smallfolliclesStart growing at once2None maturesSo they stallpart-grown3No egg releasedNo ovulation that month4With treatmentOne folliclematures andreleases its eggWhat happens in a PCOS ovaryPCOS: 1 many small follicles start growing; 2 none is picked to mature, so they stall part-grown; 3 no egg is released, no ovulation that month; 4 treatment helps one follicle mature and release its egg.1Many small folliclesStart growing at once2None maturesSo they stall part-grown3No egg releasedNo ovulation that month4With treatmentOne follicle matures andreleases its egg
  1. Many small follicles start growing
  2. None is picked to mature, so they stall part-grown
  3. No egg is released — No ovulation that month
  4. Treatment helps one follicle mature and release its egg
Diagram of a PCOS ovary: many small follicles that stopped growing, compared with a normal cycle where one follicle grows and releases an egg · Condition · where it happens

Urgent: same-day care

On fertility injections and feeling very unwell?

  • Call us the same day if you are having injections or have just had egg collection and notice a swollen, tight tummy, vomiting, passing much less urine, or breathlessness. These can be signs of ovarian hyperstimulation (OHSS). Outside clinic hours, call 108 or go to the nearest emergency department, then call us on +91 89399 94244.
01

What is PCOS?

PCOS is a hormonal and metabolic condition in which ovulation is irregular or absent, male-type hormones (androgens) run higher, and the ovaries hold many small follicles.

Underneath much of it sits insulin resistance: the body makes more insulin, and more insulin pushes the ovary to make more androgen, which stops one follicle being picked each month. It is a spectrum, from slightly long cycles to months without a period. Slim women can have it too. In 2026 an international consensus renamed it PMOS (polyendocrine metabolic ovarian syndrome), to reflect that it affects the whole body.

PCOS and trying to conceive, including lean PCOS
02

Can you get pregnant with PCOS?

Yes. Many women with PCOS conceive naturally, and most who need help respond to simple treatment.

The core problem is ovulation. No ovulation means no egg to fertilise, and no reliable day to time intercourse to. The eggs themselves are usually not the problem, and women with PCOS are generally not short of them. That is good news: the task is to restore ovulation, not replace what is missing.

03

How is PCOS diagnosed, and what is it not?

PCOS is diagnosed when at least two of three signs are present (irregular ovulation, high androgens on a blood test or on the skin, polycystic-looking ovaries on a scan) and look-alike conditions are ruled out.

Thyroid disease and a raised prolactin can look the same and are treated differently, so both are checked. Three things PCOS is not. The 'cysts' are not cysts: they are follicles that stopped growing and never need draining. PCOD is not a separate, milder disease; ask which signs you actually meet. And PCOS is not infertility.

Honest note

'Cyst dissolving' foods, drinks and packages do not exist. There is nothing to dissolve. Weight, sleep and activity can restore ovulation; no single food can. (What the evidence says)

PCOD: read this in Tamil
04

How is PCOS treated when you want a baby?

Treatment is a ladder: weight and metabolic health first, then ovulation tablets such as letrozole with scans, then low-dose injections, and IVF only if those do not work.

For women carrying extra weight, a modest, steady loss can restore ovulation on its own. Targets are set with your doctor, not from a chart. Letrozole is now generally preferred to clomiphene as the first tablet, and every cycle is tracked on scans. If tablets fail, low-dose injections follow, often with IUI when tubes are open and the sperm sample is good.

Honest note

Lifestyle, led by a healthy weight. Then smoking, alcohol, about seven hours of sleep, stress, folic acid, and correcting thyroid, diabetes, blood pressure and vitamin D. (Dr Vani Sundarapandian, on the factors couples can influence most)

Ovulation induction: tablets with scans
05

What are the risks of fertility treatment with PCOS?

PCOS ovaries react strongly to fertility drugs, so the two risks to watch are ovarian hyperstimulation (OHSS) and twins or more.

That is why doses start low and scans are frequent. A cycle with too many mature follicles is stopped, not continued. In IVF, women with PCOS often make many eggs, so embryos are usually frozen and transferred in a later cycle, which lowers the OHSS risk.

06

Does PCOS matter after pregnancy?

Yes. PCOS is a lifelong metabolic condition linked to type 2 diabetes, high cholesterol and, if periods stay absent for long, a thickened womb lining.

In pregnancy it raises the chance of gestational diabetes and high blood pressure, so tell your obstetrician early. Outside pregnancy, periodic checks of blood sugar, blood pressure and cholesterol are worth doing, and long gaps without a period need a plan.

Does this sound like you?

Do any of these sound like you?

  • Periods more than 35 days apart, or none for months
  • Acne or extra facial hair
  • Told I have PCOD, or 'cysts' on a scan
  • Weight that won't shift, however hard I try
  • Trying for 6 months with irregular periods
Yes, ask Dr Vani's team

Periods irregular for another reason, such as thyroid or stress? Start here.

The order we try them in.

  1. 1

    Weight, sleep and metabolic care

    The only step that treats the cause. Metformin is sometimes added when insulin resistance is marked. Targets are set with your doctor.

  2. 2

    Letrozole tablets, with scans

    A few days of tablets early in the cycle, then scans to see one follicle grow and time intercourse.

  3. 3

    Low-dose injections, often with IUI

  4. 4

    Doses start low and rise slowly, because PCOS ovaries are sensitive. IUI is added when tubes are open.

    When the steps above have not worked, or there is another factor such as blocked tubes, low sperm count or age. Embryos are usually frozen for a later transfer.

  5. Note

    Ovarian drilling

    A keyhole procedure for women who do not respond to tablets. Used selectively, because it can reduce egg reserve if overdone. [CONFIRM: offered at Jananam]

Your first visit

1

Talk

Your cycle pattern, weight history, skin and hair changes, and how long you've been trying.

2

Test

Pelvic scan, hormone tests including thyroid and prolactin, AMH, a tube check, and his semen analysis.

3

Plan

Where you start on the ladder, how many cycles at each step, and what we watch for.

4

Treat

Tablets with scans first for most women. Injections or IVF only if they are needed.

Questions patients ask

Still unsure? Ask us on WhatsApp — a real person replies.

Can I get pregnant naturally with PCOS?

Yes, many women with PCOS conceive without treatment, especially when cycles are only mildly irregular. If your periods are irregular, get checked after 6 months of trying rather than waiting a year.

When should I take a pregnancy test with PCOS?

If you don't know when your period is due, take a home test at least 21 days after unprotected sex; PCOS itself does not cause a false positive. During treatment, use the blood test date we give you, because a trigger injection can show a false positive if you test too early.

Does PCOS mean I will need IVF?

No. IVF is the last rung of the ladder, not the first. Most women with PCOS who need help respond to weight changes, tablets or low-dose injections.

Will losing weight cure my PCOS?

Weight loss does not cure PCOS, but for women carrying extra weight it often restores ovulation and makes every other treatment work better. Your doctor sets a realistic target with you.

Do the cysts in PCOS need to be removed?

No. They are stalled follicles, not true cysts. Removing them is not a treatment for PCOS and can damage healthy ovarian tissue.

My AMH is very high. Is that good?

A high AMH in PCOS reflects many small follicles, not better egg quality. It warns us that your ovaries may over-respond to stimulation, so doses are planned lower.

Is PCOD the same as PCOS or PMOS?

Yes, they describe the same condition. PCOD is an older term still common in India, and PMOS is the new international name agreed in 2026.

In their words, not ours.

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Sources (4)
  1. ESHRE, with Monash University: International evidence-based guideline for the assessment and management of PCOS (2023)
  2. World Health Organization: Polycystic ovary syndrome fact sheet
  3. NHS: Polyendocrine metabolic ovarian syndrome (PMOS)
  4. ASRM: PCOS is now PMOS: understanding the name change

Where to next

Start on the lowest step that can work.

Tell us about your cycles and how long you've been trying. A real person from Dr Vani's team replies on WhatsApp, usually within minutes during clinic hours (Mon to Sat, 9am to 5pm. Sunday closed.).

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